This page lists techniques and measurements employed by
the easyTEL+ system for mice, and used in the area
of measuring cardiovascular and neurological outcomes.
Physiological measurements are captured, amplified and digitized by a transmitter
surgically implanted and wirelessly transmitted to a receiver within 1.5 to 3 meters distance.
When received by the telemetry receiver, physiological signals can directly be sent to the acquisition computer, via Ethernet.
Communication between implants and receivers is bidirectional, allowing data collections, but also implant remote control (implant state (on/off), settings and configuration).
Digital Telemetry technique ensures no cross talk between transmitters, allowing
animals to be group-housed in the same room or cage.
Electrocardiogram (ECG) or electroencephalogram (EEG) signals can be retrieved using digital telemetry easyTEL+ through implanted electrodes. Various configurations are available:
To get 1 EEG or 1-lead ECG (Lead II placement is usually chosen (but not necessarily).
Unipolar configuration, using 3 wires electrodes
The reference electrode is common to both biopotentials.
Biop 1 = Electrode 1 – Electrode 2
Biop 2 = Electrode 3 – Electrode 2
Bipolar configuration, using 4 wires electrodes
In this configuration, the biopotential is measured between the positive and negative electrode, allowing to get two independent biopotentials (2 EEG).
Biop 1 = Electrode 1- Electrode 2
Biop 2 = Electrode 3- Electrode 4
The easyTEL+ implant houses a cutting-edge sensor that continuously monitors core body temperature with an accuracy of 0.1°C and a resolution of 0.04°C.
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